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Induction of a high-titered antibody response using HIV gag-EV71 VP1-based virus-like particles with the capacity to protect newborn mice challenged with a lethal dose of enterovirus 71

Enterovirus 71 (EV71) is the most frequently detected causative agent in hand, foot, and mouth disease (HFMD) and is a serious threat to public health in the Asia-Pacific region. Many EV71 vaccines are under development worldwide, and although both inactivated virus vaccines and virus-like particles...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Arch Virol
Hauptverfasser: Wang, Xi, Dong, Ke, Long, Min, Lin, Fang, Gao, Zhaowei, Wang, Lin, Zhang, Zhe, Chen, Xi, Dai, Ying, Wang, Huiping, Zhang, Huizhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Vienna 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999152/
https://ncbi.nlm.nih.gov/pubmed/29582164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-018-3797-7
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