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Anti-tumor activity of phenoxybenzamine and its inhibition of histone deacetylases

The principal finding from this study was the recognition that the α-adrenergic antagonist, phenoxybenzamine, possesses histone deacetylase inhibitory activity. Phenoxybenzamine is approved by the United States Food and Drug Administration for the treatment of hypertensive crises associated with tum...

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Detalhes bibliográficos
Publicado no:PLoS One
Autor principal: Inchiosa, Mario A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999115/
https://ncbi.nlm.nih.gov/pubmed/29897996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198514
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