Neuronal expression of the mitochondrial protein prohibitin confers profound neuroprotection in a mouse model of focal cerebral ischemia

The mitochondrial protein prohibitin (PHB) has emerged as an important modulator of neuronal survival in different injury modalities. We previously showed that viral gene transfer of PHB protects CA1 neurons from delayed neurodegeneration following transient forebrain ischemia through mitochondrial...

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Publicat a:J Cereb Blood Flow Metab
Autors principals: Kahl, Anja, Anderson, Corey J, Qian, Liping, Voss, Henning, Manfredi, Giovanni, Iadecola, Costantino, Zhou, Ping
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2017
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999007/
https://ncbi.nlm.nih.gov/pubmed/28714328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17720371
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