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Neuronal expression of the mitochondrial protein prohibitin confers profound neuroprotection in a mouse model of focal cerebral ischemia

The mitochondrial protein prohibitin (PHB) has emerged as an important modulator of neuronal survival in different injury modalities. We previously showed that viral gene transfer of PHB protects CA1 neurons from delayed neurodegeneration following transient forebrain ischemia through mitochondrial...

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Bibliografiske detaljer
Udgivet i:J Cereb Blood Flow Metab
Main Authors: Kahl, Anja, Anderson, Corey J, Qian, Liping, Voss, Henning, Manfredi, Giovanni, Iadecola, Costantino, Zhou, Ping
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999007/
https://ncbi.nlm.nih.gov/pubmed/28714328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17720371
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