OC-STAMP promotes osteoclast fusion for pathogenic bone resorption in periodontitis via up-regulation of permissive fusogen CD9

Cell fusion–mediated formation of multinuclear osteoclasts (OCs) plays a key role in bone resorption. It is reported that 2 unique OC-specific fusogens [i.e., OC-stimulatory transmembrane protein (OC-STAMP) and dendritic cell–specific transmembrane protein (DC-STAMP)], and permissive fusogen CD9, ar...

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Vydáno v:FASEB J
Hlavní autoři: Ishii, Takenobu, Ruiz-Torruella, Montserrat, Ikeda, Atsushi, Shindo, Satoru, Movila, Alexandru, Mawardi, Hani, Albassam, Abdullah, Kayal, Rayyan A., Al-Dharrab, Ayman A., Egashira, Kenji, Wisitrasameewong, Wichaya, Yamamoto, Kenta, Mira, Abdulghani I., Sueishi, Kenji, Han, Xiaozhe, Taubman, Martin A., Miyamoto, Takeshi, Kawai, Toshihisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998976/
https://ncbi.nlm.nih.gov/pubmed/29533736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201701424R
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