TRAP-positive osteoclast precursors mediate ROS/NO-dependent bactericidal activity via TLR4

Osteoclastogenesis was induced by RANKL stimulation in mouse monocytes to examine the possible bactericidal function of osteoclast precursors (OCp) and mature osteoclasts (OCm) relative to their production of NO and ROS. Tartrate-resistant acid phosphatase (TRAP)-positive OCp, but few or no OCm, pha...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Nishimura, Kazuaki, Shindo, Satoru, Movila, Alexandru, Kayal, Rayyan, Abdullah, Albassam, Savitri, Irma Josefina, Ikeda, Atsushi, Yamaguchi, Tsuguno, Howait, Mohammed, Al-dharrab, Ayman, Mira, Abdulghani, Han, Xiaozhe, Kawai, Toshihisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654318/
https://ncbi.nlm.nih.gov/pubmed/27343691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.06.021
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