TRAP-positive osteoclast precursors mediate ROS/NO-dependent bactericidal activity via TLR4

Osteoclastogenesis was induced by RANKL stimulation in mouse monocytes to examine the possible bactericidal function of osteoclast precursors (OCp) and mature osteoclasts (OCm) relative to their production of NO and ROS. Tartrate-resistant acid phosphatase (TRAP)-positive OCp, but few or no OCm, pha...

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Vydáno v:Free Radic Biol Med
Hlavní autoři: Nishimura, Kazuaki, Shindo, Satoru, Movila, Alexandru, Kayal, Rayyan, Abdullah, Albassam, Savitri, Irma Josefina, Ikeda, Atsushi, Yamaguchi, Tsuguno, Howait, Mohammed, Al-dharrab, Ayman, Mira, Abdulghani, Han, Xiaozhe, Kawai, Toshihisa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654318/
https://ncbi.nlm.nih.gov/pubmed/27343691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.06.021
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