TRAP-positive osteoclast precursors mediate ROS/NO-dependent bactericidal activity via TLR4

Osteoclastogenesis was induced by RANKL stimulation in mouse monocytes to examine the possible bactericidal function of osteoclast precursors (OCp) and mature osteoclasts (OCm) relative to their production of NO and ROS. Tartrate-resistant acid phosphatase (TRAP)-positive OCp, but few or no OCm, pha...

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Veröffentlicht in:Free Radic Biol Med
Hauptverfasser: Nishimura, Kazuaki, Shindo, Satoru, Movila, Alexandru, Kayal, Rayyan, Abdullah, Albassam, Savitri, Irma Josefina, Ikeda, Atsushi, Yamaguchi, Tsuguno, Howait, Mohammed, Al-dharrab, Ayman, Mira, Abdulghani, Han, Xiaozhe, Kawai, Toshihisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654318/
https://ncbi.nlm.nih.gov/pubmed/27343691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.06.021
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