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Feedback regulation in a stem cell model with acute myeloid leukaemia

BACKGROUND: The haematopoietic lineages with leukaemia lineages are considered in this paper. In particular, we mainly consider that haematopoietic lineages are tightly controlled by negative feedback inhibition of end-product. Actually, leukemia has been found 100 years ago. Up to now, the exact me...

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Detalles Bibliográficos
Publicado en:BMC Syst Biol
Main Authors: Jiao, Jianfeng, Luo, Min, Wang, Ruiqi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998901/
https://ncbi.nlm.nih.gov/pubmed/29745850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0561-2
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