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Modulation of the expression of genes related to the system of amyloid-beta metabolism in the brain as a novel mechanism of ceftriaxone neuroprotective properties
BACKGROUND: The dominant hypothesis about the pathogenesis of Alzheimer’s disease (AD) is the “amyloid cascade” concept and modulating the expression of proteins involved in the metabolism of amyloid-beta (Aβ) is proposed as an effective strategy for the prevention and therapy of AD. Recently, we fo...
Zapisane w:
Wydane w: | BMC Neurosci |
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Główni autorzy: | , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
BioMed Central
2018
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5998892/ https://ncbi.nlm.nih.gov/pubmed/29745864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0412-5 |
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