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Origins of the mechanochemical coupling of peptide bond formation to protein synthesis

Mechanical forces acting on the ribosome can alter the speed of protein synthesis, indicating that mechanochemistry can contribute to translation control of gene expression. The naturally occurring sources of these mechanical forces, the mechanism by which they are transmitted 10 nm to the ribosome’...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Fritch, Benjamin, Kosolapov, Andrey, Hudson, Phillip, Nissley, Daniel A., Woodcock, H. Lee, Deutsch, Carol, O’Brien, Edward P.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998662/
https://ncbi.nlm.nih.gov/pubmed/29577725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11044
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