Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice

Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction of cross-reactive and at the same time neutra...

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Publicado no:Virology
Main Authors: Krapchev, Vasil B., Rychłowska, Malgorzata, Chmielewska, Alicja, Zimmer, Karolina, Patel, Arvind H., Bieńkowska-Szewczyk, Krystyna
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998380/
https://ncbi.nlm.nih.gov/pubmed/29631174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.03.026
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