Combined Adenovirus Vector and Hepatitis C Virus Envelope Protein Prime-Boost Regimen Elicits T Cell and Neutralizing Antibody Immune Responses

Despite the recent progress in the development of new antiviral agents, hepatitis C virus (HCV) infection remains a major global health problem, and there is a need for a preventive vaccine. We previously reported that adenoviral vectors expressing HCV nonstructural proteins elicit protective T cell...

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Main Authors: Chmielewska, Alicja M., Naddeo, Mariarosaria, Capone, Stefania, Ammendola, Virginia, Hu, Ke, Meredith, Luke, Verhoye, Lieven, Rychlowska, Malgorzata, Rappuoli, Rino, Ulmer, Jeffrey B., Colloca, Stefano, Nicosia, Alfredo, Cortese, Riccardo, Leroux-Roels, Geert, Balfe, Peter, Bienkowska-Szewczyk, Krystyna, Meuleman, Philip, McKeating, Jane A., Folgori, Antonella
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019094/
https://ncbi.nlm.nih.gov/pubmed/24599994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03574-13
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