Preliminary Investigation of Focused Ultrasound-Facilitated Drug Delivery for the Treatment of Leptomeningeal Metastases

Leptomeningeal metastases (LM) are a serious complication of cancer in the central nervous system (CNS) and are diagnosed in approximately 5% of patients with solid tumors. Effective treatment using systemically administered therapeutics is hindered by the barriers of the CNS. Ultrasound can mediate...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: O’Reilly, Meaghan A., Chinnery, Tricia, Yee, My-Linh, Wu, Sheng-Kai, Hynynen, Kullervo, Kerbel, Robert S., Czarnota, Gregory J., Pritchard, Kathleen I., Sahgal, Arjun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998139/
https://ncbi.nlm.nih.gov/pubmed/29899537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27335-y
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