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MRI-guided Disruption of the Blood-brain Barrier using Transcranial Focused Ultrasound in a Rat Model

Focused ultrasound (FUS) disruption of the blood-brain barrier (BBB) is an increasingly investigated technique for circumventing the BBB(1-5). The BBB is a significant obstacle to pharmaceutical treatments of brain disorders as it limits the passage of molecules from the vasculature into the brain t...

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Autors principals: O'Reilly, Meaghan A., Waspe, Adam C., Chopra, Rajiv, Hynynen, Kullervo
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399466/
https://ncbi.nlm.nih.gov/pubmed/22433937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3555
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