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Focused-Ultrasound Disruption of the Blood-Brain Barrier Using Closely-Timed Short Pulses: Influence of Sonication Parameters and Injection Rate
Blood brain barrier disruption (BBBD) shows promise for drug delivery in the brain, however optimal parameters for disruption have yet to be firmly established. Previous work has shown that BBBD can be achieved using bursts comprised of microsecond length pulses at 50% duty cycle in order to elimina...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062725/ https://ncbi.nlm.nih.gov/pubmed/21376455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2011.01.008 |
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