A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling

Several studies have demonstrated the remarkable properties of microbiota and their metabolites in the pathogenesis of several inflammatory diseases. 10-Hydroxy-cis-12-octadecenoic acid (HYA), a bioactive metabolite generated by probiotic microorganisms during the process of fatty acid metabolism, h...

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Publicado en:Sci Rep
Autores principales: Yamada, Miki, Takahashi, Naoki, Matsuda, Yumi, Sato, Keisuke, Yokoji, Mai, Sulijaya, Benso, Maekawa, Tomoki, Ushiki, Tatsuo, Mikami, Yoshikazu, Hayatsu, Manabu, Mizutani, Yusuke, Kishino, Shigenobu, Ogawa, Jun, Arita, Makoto, Tabeta, Koichi, Maeda, Takeyasu, Yamazaki, Kazuhisa
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998053/
https://ncbi.nlm.nih.gov/pubmed/29899364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27408-y
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