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The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity
Ion channels are well placed to transduce environmental cues into signals used by cells to generate a wide range of responses, but little is known about their role in the regulation of RNA metabolism. Here we show that the TRPV4 cation channel binds the DEAD-box RNA helicase DDX3X and regulates its...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5998047/ https://ncbi.nlm.nih.gov/pubmed/29899501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04776-7 |
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