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Cytotoxic, DNA Cleavage and Pharmacokinetic Parameter Study of Substituted Novel Furan C-2 Quinoline Coupled 1, 2, 4-Triazole and Its Analogs

BACKGROUND: Furan, quinoline and triazoles are known for their wide spectrum biologically active molecules. A series of novel furan C-2 quinoline and 1, 2, 4-triazole (FQT) coupled hybrids were designed and synthesized to evaluate for their DNA cleavage and cytotoxic studies. OBJECTIVES: In this wor...

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Detalhes bibliográficos
Publicado no:Open Med Chem J
Main Authors: Anantacharya, Rajpurohit, Satyanarayan, Nayak D., Kalal, Bhuvanesh Sukhlal, Pai, Vinitha Ramanath
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997846/
https://ncbi.nlm.nih.gov/pubmed/30008962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874104501812010060
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