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The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition
Monoacylglycerol lipases (MGLs) are enzymes that hydrolyze monoacylglycerol into a free fatty acid and glycerol. Fatty acids can be used for triacylglycerol synthesis, as energy source, as building blocks for energy storage, and as precursor for membrane phospholipids. In Mycobacterium tuberculosis,...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5997763/ https://ncbi.nlm.nih.gov/pubmed/29895832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27051-7 |
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