Dropping anchor: attachment of peptidylarginine deiminase via A-LPS to secreted outer membrane vesicles of Porphyromonas gingivalis

The periodontal pathogen Porphyromonas gingivalis has been invoked in the autoimmune disease rheumatoid arthritis (RA). This association relates to the peptidylarginine deiminase of P. gingivalis (PPAD), an enzyme capable of citrullinating human proteins and potentially contributing to loss of toler...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Gabarrini, Giorgio, Heida, Rick, van Ieperen, Nienke, Curtis, Mike A., van Winkelhoff, Arie Jan, van Dijl, Jan Maarten
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997701/
https://ncbi.nlm.nih.gov/pubmed/29895934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27223-5
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