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Universal response in the RKO colon cancer cell line to distinct antimitotic therapies

Both classic and newer antimitotics commonly induce a prolonged mitotic arrest in cell culture. During arrest, cells predominantly undergo one of two fates: cell death by apoptosis, or mitotic slippage and survival. To refine this binary description, a quantitative understanding of these cell respon...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lorz, Alexander, Botesteanu, Dana-Adriana, Levy, Doron
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997697/
https://ncbi.nlm.nih.gov/pubmed/29895957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27267-7
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