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Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity

Krüppel-like factor 4 (KLF4) is a zinc-finger-containing transcription factor, the expression of which is enriched in the postmitotic cells of the intestinal epithelium. KLF4 is a target gene of the tumor suppressor adenomatous polyposis coli (APC). We sought to determine the role of KLF4 in suppres...

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Bibliografiska uppgifter
Huvudupphovsmän: Dang, Duyen T, Chen, Xinming, Feng, Jing, Torbenson, Michael, Dang, Long H, Yang, Vincent W
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275074/
https://ncbi.nlm.nih.gov/pubmed/12776194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1206413
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