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MALDI Imaging Mass Spectrometry of N-glycans and Tryptic Peptides from the Same Formalin-Fixed, Paraffin-Embedded Tissue Section

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a unique and well developed tool for probing the protein content of formalin-fixed, paraffin-embedded tissue (FFPE). Integral to this approach is the application of trypsin, and more recently peptide N-glycosidase...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Autores principales: Angel, Peggi M., Mehta, Anand, Norris-Caneda, Kim, Drake, Richard R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997529/
https://ncbi.nlm.nih.gov/pubmed/29058228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/7651_2017_81
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