Multiplexed Imaging Mass Spectrometry of the Extracellular Matrix using Serial Enzyme Digests from Formalin-Fixed Paraffin Embedded Tissue Sections

We report a multiplexed imaging mass spectrometry method which spatially localizes and selectively accesses the extracellular matrix on formalin-fixed paraffin-embedded tissue sections. The extracellular matrix (ECM) consists of 1) fibrous proteins, post-translationally modified (PTM) via N- and O-l...

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Bibliographic Details
Published in:Anal Bioanal Chem
Main Authors: Clift, Cassandra L., Drake, Richard R., Mehta, Anand, Angel, Peggi M.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012227/
https://ncbi.nlm.nih.gov/pubmed/33206215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-020-03047-z
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