Macrophage P2X4 receptors augment bacterial killing and protect against sepsis

The macrophage is a major phagocytic cell type, and its impaired function is a primary cause of immune paralysis, organ injury, and death in sepsis. An incomplete understanding of the endogenous molecules that regulate macrophage bactericidal activity is a major barrier for developing effective ther...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Csóka, Balázs, Németh, Zoltán H., Szabó, Ildikó, Davies, Daryl L., Varga, Zoltán V., Pálóczi, János, Falzoni, Simonetta, Di Virgilio, Francesco, Muramatsu, Rieko, Yamashita, Toshihide, Pacher, Pál, Haskó, György
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997389/
https://ncbi.nlm.nih.gov/pubmed/29875325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99431
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