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Arf6 and its ZEB1-EPB41L5 mesenchymal axis are required for both mesenchymal- and amoeboid-type invasion of cancer cells

Modes of cancer invasion interchange between the mesenchymal type and amoeboid type in response to the microenvironment, in which RhoA and Rac1 are selectively required to perform different modes of actin-cytoskeletal remodeling. Membrane remodeling is another integral part of invasion. Arf6 regulat...

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Bibliografiske detaljer
Udgivet i:Small GTPases
Main Authors: Handa, Haruka, Hashimoto, Ari, Hashimoto, Shigeru, Sabe, Hisataka
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997150/
https://ncbi.nlm.nih.gov/pubmed/27754741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1249043
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