Advancements in the oral delivery of Docetaxel: challenges, current state-of-the-art and future trends

The oral delivery of cancer chemotherapeutic drugs is challenging due to low bioavailability, gastrointestinal side effects, first-pass metabolism and P-glycoprotein efflux pumps. Thus, chemotherapeutic drugs, including Docetaxel, are administered via an intravenous route, which poses many disadvant...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Sohail, Muhammad Farhan, Rehman, Mubashar, Sarwar, Hafiz Shoaib, Naveed, Sara, Salman, Omer, Bukhari, Nadeem Irfan, Hussain, Irshad, Webster, Thomas J, Shahnaz, Gul
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997133/
https://ncbi.nlm.nih.gov/pubmed/29922053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S164518
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