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Advancements in the oral delivery of Docetaxel: challenges, current state-of-the-art and future trends
The oral delivery of cancer chemotherapeutic drugs is challenging due to low bioavailability, gastrointestinal side effects, first-pass metabolism and P-glycoprotein efflux pumps. Thus, chemotherapeutic drugs, including Docetaxel, are administered via an intravenous route, which poses many disadvant...
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| Publicado no: | Int J Nanomedicine |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5997133/ https://ncbi.nlm.nih.gov/pubmed/29922053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S164518 |
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