MassARRAY-based simultaneous detection of hotspot somatic mutations and recurrent fusion genes in papillary thyroid carcinoma: the PTC-MA assay

PURPOSE: We exploited the MassARRAY (MA) genotyping platform to develop the “PTC-MA assay”, which allows the simultaneous detection of 13 hotspot mutations, in the BRAF, KRAS, NRAS, HRAS, TERT, AKT1, PIK3CA, and EIF1AX genes, and six recurrent genetic rearrangements, involving the RET and TRK genes...

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Bibliographic Details
Published in:Endocrine
Main Authors: Pesenti, Chiara, Muzza, Marina, Colombo, Carla, Proverbio, Maria Carla, Farè, Claudia, Ferrero, Stefano, Miozzo, Monica, Fugazzola, Laura, Tabano, Silvia
Format: Artigo
Language:Inglês
Published: Springer US 2017
Subjects:
Endocrine Methods and Techniques
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997117/
https://ncbi.nlm.nih.gov/pubmed/29214440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-017-1483-2
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