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Combined Mutational and Clonality Analyses Support the Existence of Intra-Tumor Heterogeneity in Papillary Thyroid Cancer

Despite its potential clinical impact, intra-tumor genetic heterogeneity (ITH) has been scantly investigated in papillary thyroid cancer (PTC). We studied ITH in PTC by combining, for the first time, data derived from the evaluation of the normalized allelic frequencies (NAF) of the mutation/s, usin...

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Detaylı Bibliyografya
Yayımlandı:J Clin Med
Asıl Yazarlar: Muzza, Marina, Pogliaghi, Gabriele, Persani, Luca, Fugazzola, Laura, Colombo, Carla
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234519/
https://ncbi.nlm.nih.gov/pubmed/34208446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10122645
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