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Combined Mutational and Clonality Analyses Support the Existence of Intra-Tumor Heterogeneity in Papillary Thyroid Cancer

Despite its potential clinical impact, intra-tumor genetic heterogeneity (ITH) has been scantly investigated in papillary thyroid cancer (PTC). We studied ITH in PTC by combining, for the first time, data derived from the evaluation of the normalized allelic frequencies (NAF) of the mutation/s, usin...

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Detalles Bibliográficos
Publicado en:J Clin Med
Main Authors: Muzza, Marina, Pogliaghi, Gabriele, Persani, Luca, Fugazzola, Laura, Colombo, Carla
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234519/
https://ncbi.nlm.nih.gov/pubmed/34208446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10122645
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