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IMiQ: a novel protein quality control compartment protecting mitochondrial functional integrity

Aggregation processes can cause severe perturbations of cellular homeostasis and are frequently associated with diseases. We performed a comprehensive analysis of mitochondrial quality and function in the presence of aggregation-prone polypeptides. Despite a significant aggregate formation inside mi...

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Publicat a:Mol Biol Cell
Autors principals: Bruderek, Michael, Jaworek, Witold, Wilkening, Anne, Rüb, Cornelia, Cenini, Giovanna, Förtsch, Arion, Sylvester, Marc, Voos, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996957/
https://ncbi.nlm.nih.gov/pubmed/29212875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0027
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