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PYNOD reduces microglial inflammation and consequent neurotoxicity upon lipopolysaccharides stimulation
PYNOD, a nod-like receptors (NLR)-like protein, was indicated to inhibit NF-κB activation, caspase-1-mediated interleukin (IL)-1β release and cell apoptosis in a dose-dependent manner. Exogenous addition of recombinant PYNOD to mixed glial cultures may suppress caspase-1 activation and IL-1β secreti...
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| Publicado no: | Exp Ther Med |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5996706/ https://ncbi.nlm.nih.gov/pubmed/29904414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6108 |
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