Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

BACKGROUND: Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. However, it is not known if or when corticosteroids can be admin...

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Udgivet i:J Immunother Cancer
Main Authors: Giles, Amber J., Hutchinson, Marsha-Kay N. D., Sonnemann, Heather M., Jung, Jinkyu, Fecci, Peter E., Ratnam, Nivedita M., Zhang, Wei, Song, Hua, Bailey, Rolanda, Davis, Dionne, Reid, Caitlin M., Park, Deric M., Gilbert, Mark R.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996496/
https://ncbi.nlm.nih.gov/pubmed/29891009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0371-5
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