Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

BACKGROUND: Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. However, it is not known if or when corticosteroids can be admin...

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Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Giles, Amber J., Hutchinson, Marsha-Kay N. D., Sonnemann, Heather M., Jung, Jinkyu, Fecci, Peter E., Ratnam, Nivedita M., Zhang, Wei, Song, Hua, Bailey, Rolanda, Davis, Dionne, Reid, Caitlin M., Park, Deric M., Gilbert, Mark R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996496/
https://ncbi.nlm.nih.gov/pubmed/29891009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0371-5
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