Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

BACKGROUND: Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. However, it is not known if or when corticosteroids can be admin...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Giles, Amber J., Hutchinson, Marsha-Kay N. D., Sonnemann, Heather M., Jung, Jinkyu, Fecci, Peter E., Ratnam, Nivedita M., Zhang, Wei, Song, Hua, Bailey, Rolanda, Davis, Dionne, Reid, Caitlin M., Park, Deric M., Gilbert, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996496/
https://ncbi.nlm.nih.gov/pubmed/29891009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0371-5
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