High Mobility Group Box 1 Promotes Aortic Calcification in Chronic Kidney Disease via the Wnt/β-Catenin Pathway

Vascular calcification (VC) is common in chronic kidney disease (CKD), where cardiovascular mortality remains the leading cause of death. Here, we examined the role of high-mobility group box1 (HMGB1), a nuclear DNA-binding protein involved in inflammation, in aortic calcification and renal dysfunct...

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Publicat a:Front Physiol
Autors principals: Jin, Xiucai, Rong, Shu, Yuan, Weijie, Gu, Lijie, Jia, Jieshuang, Wang, Ling, Yu, Honglei, Zhuge, Yifeng
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996195/
https://ncbi.nlm.nih.gov/pubmed/29922171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00665
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