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High mobility group box 1 induces calcification of aortic valve interstitial cells via toll-like receptor 4

Chronic inflammation and the calcification of aortic valve interstitial cells (AVICs) are the primary etiologies of calcific aortic valve disease (CAVD). However, the underlying mechanism remains to be elucidated. The present study investigated the importance of high mobility group box 1 (HMGB1) via...

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Dettagli Bibliografici
Pubblicato in:Mol Med Rep
Autori principali: Shen, Wenjun, Zhou, Jianqing, Wang, Chaoyang, Xu, Guangze, Wu, Ying, Hu, Zhaohui
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428883/
https://ncbi.nlm.nih.gov/pubmed/28260034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6287
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