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Using Gene Expression to Annotate Cardiovascular GWAS Loci

Genetic variants at hundreds of loci associated with cardiovascular phenotypes have been identified by genome wide association studies. Most of these variants are located in intronic or intergenic regions rendering the functional and mechanistic follow up difficult. These non-protein-coding regions...

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Vydáno v:Front Cardiovasc Med
Hlavní autor: Heinig, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996083/
https://ncbi.nlm.nih.gov/pubmed/29922679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2018.00059
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