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Predicting gene ontology annotations of orphan GWAS genes using protein-protein interactions

BACKGROUND: The number of genome-wide association studies (GWAS) has increased rapidly in the past couple of years, resulting in the identification of genes associated with different diseases. The next step in translating these findings into biomedically useful information is to find out the mechani...

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Autors principals: Kuppuswamy, Usha, Ananthasubramanian, Seshan, Wang, Yanli, Balakrishnan, Narayanaswamy, Ganapathiraju, Madhavi K
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124845/
https://ncbi.nlm.nih.gov/pubmed/24708602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-9-10
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