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Aberrant DNA methylation of the p16, APC, MGMT, TIMP3 and CDH1 gene promoters in tumours and the surgical margins of patients with oral cavity cancer

Oral cavity cancer is a type of head and neck squamous cell carcinoma (HNSCC) and contributes to significant morbidity and mortality each year. An epigenetic pathway of transcriptional inactivation for many genes has been described in various cancers, including HNSCC. For our study, we selected gene...

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Détails bibliographiques
Publié dans:J Cancer
Auteurs principaux: Strzelczyk, Joanna Katarzyna, Krakowczyk, Łukasz, Owczarek, Aleksander Jerzy
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995944/
https://ncbi.nlm.nih.gov/pubmed/29896273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.24477
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