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β-apo-10′-carotenoids support normal embryonic development during vitamin A deficiency

Vitamin A deficiency is still a public health concern affecting millions of pregnant women and children. Retinoic acid, the active form of vitamin A, is critical for proper mammalian embryonic development. Embryos can generate retinoic acid from maternal circulating β-carotene upon oxidation of reti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Spiegler, Elizabeth, Kim, Youn-Kyung, Hoyos, Beatrice, Narayanasamy, Sureshbabu, Jiang, Hongfeng, Savio, Nicole, Curley, Robert W., Harrison, Earl H., Hammerling, Ulrich, Quadro, Loredana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995931/
https://ncbi.nlm.nih.gov/pubmed/29892071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27071-3
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