β-Apo-10′-carotenoids Modulate Placental Microsomal Triglyceride Transfer Protein Expression and Function to Optimize Transport of Intact β-Carotene to the Embryo

β-Carotene is an important source of vitamin A for the mammalian embryo, which depends on its adequate supply to achieve proper organogenesis. In mammalian tissues, β-carotene 15,15′-oxygenase (BCO1) converts β-carotene to retinaldehyde, which is then oxidized to retinoic acid, the biologically acti...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Costabile, Brianna K., Kim, Youn-Kyung, Iqbal, Jahangir, Zuccaro, Michael V., Wassef, Lesley, Narayanasamy, Sureshbabu, Curley, Robert W., Harrison, Earl H., Hussain, M. Mahmood, Quadro, Loredana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000097/
https://ncbi.nlm.nih.gov/pubmed/27402843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738336
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