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Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface
The limitations of current anti-angiogenic therapies necessitate other targets with complimentary mechanisms. Here, we show for the first time that soluble E-cadherin (sE-cad) (an 80-kDa soluble form), which is highly expressed in the malignant ascites of ovarian cancer patients, is a potent inducer...
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| Опубликовано в: : | Nat Commun |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995921/ https://ncbi.nlm.nih.gov/pubmed/29891938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04695-7 |
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