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A charge-sensing region in the stromal interaction molecule 1 luminal domain confers stabilization-mediated inhibition of SOCE in response to S-nitrosylation

Store-operated Ca(2+) entry (SOCE) is a major Ca(2+) signaling pathway facilitating extracellular Ca(2+) influx in response to the initial release of intracellular endo/sarcoplasmic reticulum (ER/SR) Ca(2+) stores. Stromal interaction molecule 1 (STIM1) is the Ca(2+) sensor that activates SOCE follo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Zhu, Jinhui, Lu, Xiangru, Feng, Qingping, Stathopulos, Peter B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995509/
https://ncbi.nlm.nih.gov/pubmed/29661937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000503
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