Conserved Noncanonical Residue Gly-126 Confers Instability to the Middle Part of the Tropomyosin Molecule

Tropomyosin (Tm) is a two-stranded α-helical coiled-coil protein with a well established role in regulation of actin cytoskeleton and muscle contraction. It is believed that many Tm functions are enabled by its flexibility whose nature has not been completely understood. We hypothesized that the wel...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nevzorov, Ilya A., Nikolaeva, Olga P., Kainov, Yaroslav A., Redwood, Charles S., Levitsky, Dmitrii I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Protein Structure and Folding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091185/
https://ncbi.nlm.nih.gov/pubmed/21454502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.209353
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