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The telomerase inhibitor AZT enhances differentiation and prevents overgrowth of human pluripotent stem cell–derived neural progenitors
Human pluripotent stem cell (hPSC)–based cell-replacement therapy has emerged as a promising approach for addressing numerous neurological diseases. However, hPSC transplantation has the potential to cause human cell overgrowth and cancer, which represents a major obstacle to implementing hPSC-based...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995503/ https://ncbi.nlm.nih.gov/pubmed/29628445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809889 |
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