CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure

Human pluripotent stem cells (hPSCs) generate hematopoietic progenitor cells (HPCs) but fail to engraft xenograft models used to detect adult/somatic hematopoietic stem cells (HSCs) from donors. Recent progress to derive hPSC-derived HSCs has relied on cell-autonomous forced expression of transcript...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Stem Cell Reports
Glavni autori: Reid, Jennifer C., Tanasijevic, Borko, Golubeva, Diana, Boyd, Allison L., Porras, Deanna P., Collins, Tony J., Bhatia, Mickie
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995456/
https://ncbi.nlm.nih.gov/pubmed/29742393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.04.003
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items