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Synergistic and non-specific nucleic acid production by T7 RNA polymerase and Bsu DNA polymerase catalyzed by single-stranded polynucleotides

Point-of-care molecular diagnostic tests show great promise for providing accurate, timely results in low-infrastructure healthcare settings and at home. The design space for these tests is limited by a variety of possible background reactions, which often originate from relatively weak promiscuous...

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Pubblicato in:Synth Syst Biotechnol
Autori principali: Emery, Nicholas J., Majumder, Sagardip, Liu, Allen P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: KeAi Publishing 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995454/
https://ncbi.nlm.nih.gov/pubmed/29900426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2018.02.005
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