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Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid

Vaccinia virus poly(A) polymerase (VP55) is the only known polymerase that can translocate independently with respect to single-stranded nucleic acid (ssNA). Previously, its structure has only been solved in the context of the VP39 processivity factor. Here, a crystal structure of unliganded monomer...

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Détails bibliographiques
Auteurs principaux: Li, Huiyung, Li, Changzheng, Zhou, Sufeng, Poulos, Thomas L., Gershon, Paul David
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606039/
https://ncbi.nlm.nih.gov/pubmed/23519670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913000346
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