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Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier

Whether iron formulations used therapeutically for a variety of conditions involving iron deficiency can deliver iron to the brain is a significant clinical question given the impact that iron loading has on the brain in neurodegenerative diseases. In this study, we examine the ability of 5 pharmace...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chiou, Brian, Neal, Emma H., Bowman, Aaron B., Lippmann, Ethan S., Simpson, Ian A., Connor, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995392/
https://ncbi.nlm.nih.gov/pubmed/29889872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198775
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