A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs

Human induced pluripotent stem cell (iPSC)-derived developmental lineages are key tools for in vitro mechanistic interrogations, drug discovery, and disease modeling. iPSCs have previously been differentiated to endothelial cells with blood-brain barrier (BBB) properties, as defined by high transend...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Neal, Emma H., Marinelli, Nicholas A., Shi, Yajuan, McClatchey, P. Mason, Balotin, Kylie M., Gullett, Dalton R., Hagerla, Kameron A., Bowman, Aaron B., Ess, Kevin C., Wikswo, John P., Lippmann, Ethan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565873/
https://ncbi.nlm.nih.gov/pubmed/31189096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.05.008
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